| NCT04454840 |
Treatment of Intravenous Infusion Plasma in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT04454840 |
Completed |
Peking University Third Hospital |
2019-05-01 |
| NCT04288856 |
Study to Assess the Safety, Tolerability, Pharmacokinetics, and Effect on Disease Progression of BIIB078 Administered to Previously Treated Adults C9ORF72-Associated Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT04288856 |
Enrolling by invitation |
Biogen |
2023-07-19 |
| NCT03427086 |
Safety and Tolerability of High Dose Biotin in Patients With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03427086 |
Recruiting |
American University of Beirut Medical Center |
2021-01-10 |
| NCT03377309 |
Safety and Tolerability of Perampanel in Amyotrophic Lateral Sclerosis Patients |
https://ClinicalTrials.gov/show/NCT03377309 |
Recruiting |
American University of Beirut Medical Center |
2022-06-01 |
| NCT03367650 |
Epidemiology and Genetics of the Amyotrophic Lateral Sclerosis in the French West Indies |
https://ClinicalTrials.gov/show/NCT03367650 |
Recruiting |
Centre Hospitalier Universitaire de Pointe-a-Pitre |
2020-05-13 |
| NCT03359538 |
Rapamycin Treatment for ALS |
https://ClinicalTrials.gov/show/NCT03359538 |
Active, not recruiting |
Azienda Ospedaliero-Universitaria di Modena |
2020-12-15 |
| NCT03326622 |
Exercise and Disease Progression in Amyotrophic Lateral Sclerosis Patients |
https://ClinicalTrials.gov/show/NCT03326622 |
Completed |
University of Lisbon |
2015-03-30 |
| NCT03324399 |
A Study of Protein Metabolism, Microbiome and Investigational Probiotic Use in Patients With ALS |
https://ClinicalTrials.gov/show/NCT03324399 |
Completed |
Avera McKennan Hospital & University Health Center |
2019-06-26 |
| NCT03321487 |
Blood-Brain Barrier Opening Using MR-Guided Focused Ultrasound in Patients With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03321487 |
Active, not recruiting |
InSightec |
2020-12-31 |
| NCT03293069 |
Conservative Iron Chelation as a Disease-modifying Strategy in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03293069 |
Recruiting |
University Hospital, Lille |
2022-03-31 |
| NCT03296501 |
Intraspinal Transplantation of Autologous ADRC in ALS Patients |
https://ClinicalTrials.gov/show/NCT03296501 |
Active, not recruiting |
Mossakowski Medical Research Centre Polish Academy of Sciences |
2020-10-31 |
| NCT03293394 |
Rehabilitative Trial With tDCS in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03293394 |
Completed |
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia |
2018-06-20 |
| NCT03280056 |
Safety and Efficacy of Repeated Administrations of NurOwn® in ALS Patients |
https://ClinicalTrials.gov/show/NCT03280056 |
Active, not recruiting |
Brainstorm-Cell Therapeutics |
2020-10-31 |
| NCT03272802 |
Treatment Effect of Edaravone in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT03272802 |
Active, not recruiting |
Isfahan University of Medical Sciences |
2019-03-16 |
| NCT03272503 |
A Clinical Trial of Pimozide in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT03272503 |
Recruiting |
University of Calgary |
2020-12-31 |
| NCT03268603 |
Intrathecal Autologous Adipose-derived Mesenchymal Stromal Cells for Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT03268603 |
Recruiting |
Mayo Clinic |
2022-12-31 |
| NCT03214146 |
Safety/Efficacy Study of 2nd Cycle Treatment After 6 Months of 1st Cycle HLA-haplo Matched Allogenic Bone Marrow Derived Stem Cell Treatment in ALS |
https://ClinicalTrials.gov/show/NCT03214146 |
Active, not recruiting |
Hanyang University Seoul Hospital |
2019-03-25 |
| NCT03204500 |
Dual Treatment With Lithium and Valproate in ALS. |
https://ClinicalTrials.gov/show/NCT03204500 |
Active, not recruiting |
El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez |
2019-04-30 |
| NCT03202017 |
Lung Volume Recruitment Combined With Expiratory Muscle Strength Training in ALS |
https://ClinicalTrials.gov/show/NCT03202017 |
Recruiting |
University of Minnesota |
2020-12-31 |
| NCT03201991 |
ALS Study Determining Various Biomarkers and Strength Comparison After Exercise |
https://ClinicalTrials.gov/show/NCT03201991 |
Completed |
University of Kansas Medical Center |
2018-04-18 |
| NCT03186040 |
Open-label Clinical Trial of Lacosamide in ALS |
https://ClinicalTrials.gov/show/NCT03186040 |
Recruiting |
Chiba University |
2020-04-30 |
| NCT03168711 |
Safety of Urate Elevation in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT03168711 |
Completed |
Massachusetts General Hospital |
2019-12-10 |
| NCT03160898 |
A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT03160898 |
Completed |
Cytokinetics |
2019-03-07 |
| NCT03136809 |
ALS Treatment Extension Study |
https://ClinicalTrials.gov/show/NCT03136809 |
Active, not recruiting |
Collaborative Medicinal Development Pty Limited |
2020-12-31 |
| NCT03127514 |
AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT03127514 |
Completed |
Amylyx Pharmaceuticals Inc. |
2019-09-25 |
| NCT03114215 |
Effect of MD1003 in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03114215 |
Completed |
MedDay Pharmaceuticals SA |
2017-06-12 |
| NCT03113630 |
Virtual Task in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03113630 |
Completed |
University of Sao Paulo |
2016-08-03 |
| NCT03095989 |
An Online Mindfulness Intervention for People With ALS and Their Caregivers |
https://ClinicalTrials.gov/show/NCT03095989 |
Completed |
Harvard University |
2019-02-28 |
| NCT03085706 |
Transplantation of Autologous Peripheral Blood Mononuclear Cells for Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03085706 |
Completed |
The First Affiliated Hospital of Dalian Medical University |
2012-12-31 |
| NCT03020797 |
A Clinical Trial to Evaluate the Safety and Efficacy of Fycompa in Subjects With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT03020797 |
Recruiting |
Stony Brook University |
2019-12-31 |
| NCT03019419 |
Perampanel for Sporadic Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT03019419 |
Active, not recruiting |
Tokyo Medical University |
2022-12-31 |
| NCT02987413 |
Escalated Application of Mesenchymal Stem Cells in Amyotrophic Lateral Sclerosis Patients |
https://ClinicalTrials.gov/show/NCT02987413 |
Completed |
Hospital e Maternidade Dr. Christóvão da Gama |
2016-03-31 |
| NCT02943850 |
CNS10-NPC-GDNF for the Treatment of ALS |
https://ClinicalTrials.gov/show/NCT02943850 |
Active, not recruiting |
Cedars-Sinai Medical Center |
2019-10-31 |
| NCT02936635 |
A Study for Patients Who Completed VITALITY-ALS (CY 4031) |
https://ClinicalTrials.gov/show/NCT02936635 |
Completed |
Cytokinetics |
2018-10-26 |
| NCT02891629 |
Safety and Feasibility of the EyeControl Device |
https://ClinicalTrials.gov/show/NCT02891629 |
Completed |
Eyefree Assisting Communication Ltd |
2017-01-28 |
| NCT02880033 |
Oxidative Stress and Apoptosis of Energy Metabolism by Deferiprone From the Circulating Lymphocytes |
https://ClinicalTrials.gov/show/NCT02880033 |
Completed |
University Hospital, Lille |
2019-10-31 |
| NCT02872142 |
Efficacy and Safety of Plasma Exchange With Albutein® 5% in Patients With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT02872142 |
Completed |
Grifols Therapeutics LLC |
2019-08-31 |
| NCT02870634 |
Phase 1 Dose Escalation and PK Study of Cu(II)ATSM in ALS/MND |
https://ClinicalTrials.gov/show/NCT02870634 |
Completed |
Collaborative Medicinal Development Pty Limited |
2019-10-30 |
| NCT02868580 |
Safety and Tolerability of Antiretroviral (Triumeq) in Patients With Amyotrophic Lateral Sclerosis (ALS). |
https://ClinicalTrials.gov/show/NCT02868580 |
Completed |
Neuroscience Trials Australia |
2017-12-31 |
| NCT02868567 |
Use of Dalfampridine in Primary Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT02868567 |
Recruiting |
Weill Medical College of Cornell University |
2021-01-31 |
| NCT02851914 |
SSRIs vs. TCAs for Depression in ALS Patients |
https://ClinicalTrials.gov/show/NCT02851914 |
Completed |
St. Louis University |
2019-05-30 |
| NCT02794857 |
Safety and Efficacy Study of NP001 in Patients With Amyotrophic Lateral Sclerosis (ALS) and Systemic Inflammation |
https://ClinicalTrials.gov/show/NCT02794857 |
Completed |
Neuraltus Pharmaceuticals, Inc. |
2017-12-12 |
| NCT02781454 |
Mexiletine in Sporadic Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT02781454 |
Completed |
University of Washington |
2018-09-30 |
| NCT02759003 |
Nightime NIV Initiation in Amyotrophic Lateral Sclerosis in an Outpatient Setting |
https://ClinicalTrials.gov/show/NCT02759003 |
Completed |
Fondazione Salvatore Maugeri |
2013-03-31 |
| NCT02750982 |
Laughter Therapy Effects on Mood, Stress and Self-efficacy in People With Neurological Diseases. |
https://ClinicalTrials.gov/show/NCT02750982 |
Completed |
Brown, Theodore R., M.D., MPH |
2018-08-31 |
| NCT02714036 |
A Biomarker Study to Evaluate MN-166 (Ibudilast) in Subjects With Amyotrophic Literal Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT02714036 |
Active, not recruiting |
MediciNova |
2019-12-31 |
| NCT02710162 |
Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT02710162 |
Completed |
University of Florida |
2017-12-19 |
| NCT02710110 |
Respiratory Strength Training in Persons With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT02710110 |
Completed |
University of Florida |
2017-11-30 |
| NCT02682030 |
The Use of Airway Clearance Devices in ALS |
https://ClinicalTrials.gov/show/NCT02682030 |
Completed |
Cedars-Sinai Medical Center |
2018-12-31 |
| NCT02670226 |
Muscular Biomarkers in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT02670226 |
Active, not recruiting |
University Hospital, Tours |
2020-09-30 |
| NCT02655614 |
A Study of GDC-0134 to Determine Initial Safety, Tolerability, and Pharmacokinetic Parameters in Participants With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT02655614 |
Active, not recruiting |
Genentech, Inc. |
2020-08-01 |
| NCT02645461 |
Acetylcholine Receptors From Human Muscles as Pharmacological Target for ALS |
https://ClinicalTrials.gov/show/NCT02645461 |
Completed |
University of Roma La Sapienza |
2015-06-30 |
| NCT02623699 |
An Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of BIIB067 in Adults With Inherited Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT02623699 |
Recruiting |
Biogen |
2021-07-06 |
| NCT02588677 |
Masitinib in Combination With Riluzole for the Treatment of Patients Suffering From Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT02588677 |
Completed |
AB Science |
2016-12-05 |
| NCT02795052 |
Neurologic Stem Cell Treatment Study |
https://ClinicalTrials.gov/show/NCT02795052 |
Recruiting |
MD Stem Cells |
2022-06-30 |
| NCT02437110 |
HERV-K Suppression Using Antiretroviral Therapy in Volunteers With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT02437110 |
Recruiting |
National Institutes of Health Clinical Center (CC) |
2022-02-01 |
| NCT02548663 |
Sport Therapy and Osteopathy Manipulative Treatment in ALS |
https://ClinicalTrials.gov/show/NCT02548663 |
Completed |
University of Milano Bicocca |
2014-12-31 |
| NCT02537132 |
“New Perspectives of Adaptation to NIV in ALS” |
https://ClinicalTrials.gov/show/NCT02537132 |
Completed |
Fondazione Don Carlo Gnocchi Onlus |
2016-04-30 |
| NCT02496767 |
Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year |
https://ClinicalTrials.gov/show/NCT02496767 |
Completed |
Cytokinetics |
2017-03-09 |
| NCT02492516 |
Intravenous Injection of Adipose Derived Mesenchymal Stem Cell for ALS |
https://ClinicalTrials.gov/show/NCT02492516 |
Completed |
Royan Institute |
2017-03-31 |
| NCT02487407 |
Effects of ODM-109 on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT02487407 |
Completed |
Orion Corporation, Orion Pharma |
2017-05-31 |
| NCT02479802 |
Efficacy and Safety of Plasma Exchange With Albumin in Patients With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT02479802 |
Completed |
Grifols Biologicals, LLC |
2016-06-30 |
| NCT02469896 |
A Trial of Tocilizumab in ALS Subjects |
https://ClinicalTrials.gov/show/NCT02469896 |
Completed |
Barrow Neurological Institute |
2018-07-11 |
| NCT02469675 |
Brain and Nerve Stimulation for Hand Muscles in Spinal Cord Injury and ALS |
https://ClinicalTrials.gov/show/NCT02469675 |
Completed |
Bronx VA Medical Center |
2018-07-31 |
| NCT02464852 |
Assessment of the Effects of Sheffield Support Snood in MND Patients |
https://ClinicalTrials.gov/show/NCT02464852 |
Completed |
Sheffield Teaching Hospitals NHS Foundation Trust |
2015-12-31 |
| NCT02464748 |
Telehealth in Motor Neurone Disease |
https://ClinicalTrials.gov/show/NCT02464748 |
Completed |
Sheffield Teaching Hospitals NHS Foundation Trust |
2016-04-30 |
| NCT02463825 |
A Registry-Based Clinical Trial of Pimozide in Patients With Neuromuscular Junction Transmission Dysfunction Due to ALS |
https://ClinicalTrials.gov/show/NCT02463825 |
Active, not recruiting |
University of Calgary |
2016-08-31 |
| NCT02460679 |
Safety and Biomarker Study of EPI-589 in Subjects With ALS |
https://ClinicalTrials.gov/show/NCT02460679 |
Completed |
Edison Pharmaceuticals Inc |
2018-07-31 |
| NCT02450552 |
Clinical Trial of Ezogabine (Retigabine) in ALS Subjects |
https://ClinicalTrials.gov/show/NCT02450552 |
Completed |
Massachusetts General Hospital |
2018-01-31 |
| NCT02447952 |
Exploratory Study of Biotelemetry in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT02447952 |
Completed |
GlaxoSmithKline |
2017-06-01 |
| NCT02418546 |
Electronic-health Application To Measure Outcomes REmotely Clinical Trial |
https://ClinicalTrials.gov/show/NCT02418546 |
Completed |
Massachusetts General Hospital |
2017-12-31 |
| NCT02383654 |
Compassionate Treatment : An Exploratory Clinical Trial to Assess Treatment of Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT02383654 |
Completed |
China Medical University Hospital |
2016-01-31 |
| NCT02313402 |
A New Eye-based Communication Device for ALS Patients |
https://ClinicalTrials.gov/show/NCT02313402 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2015-04-30 |
| NCT02306590 |
Efficacy, Safety and Tolerability of High Lipid and Calorie Supplementation in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT02306590 |
Completed |
University of Ulm |
2018-01-31 |
| NCT02306109 |
Effect of Motor Rehabilitation Treatment on Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT02306109 |
Completed |
Azienda Unita’ Sanitaria Locale Di Modena |
2017-12-31 |
| NCT02290886 |
A Multicenter Phase I/II Clinical Trial to Evaluate Safety of Mesenchymal Stem Cell in Patients With Amyotrophic Sclerosis Lateral |
https://ClinicalTrials.gov/show/NCT02290886 |
Active, not recruiting |
Andalusian Network for Design and Translation of Advanced Therapies |
2020-12-31 |
| NCT02288091 |
A Pilot Study of Inosine in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT02288091 |
Completed |
Massachusetts General Hospital |
2016-03-31 |
| NCT02238626 |
Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT02238626 |
Completed |
MediciNova |
2017-08-31 |
| NCT02236897 |
PET Imaging in ALS Patients |
https://ClinicalTrials.gov/show/NCT02236897 |
Completed |
Johns Hopkins University |
2017-03-31 |
| NCT02236065 |
Combination Therapy of Cord Blood and G-CSF for Patients With Brain Injury or Neurodegenerative Disorders |
https://ClinicalTrials.gov/show/NCT02236065 |
Completed |
Bundang CHA Hospital |
2016-07-31 |
| NCT02166944 |
Tamoxifen Treatment in Patients With Motor Neuron Disease |
https://ClinicalTrials.gov/show/NCT02166944 |
Completed |
Taipei Medical University Shuang Ho Hospital |
2019-09-17 |
| NCT02164253 |
Focal Accumulation of Iron in Cerebral Regions in Early ALS (Amyotrophic Lateral Sclerosis) Patients |
https://ClinicalTrials.gov/show/NCT02164253 |
Completed |
University Hospital, Lille |
2016-12-31 |
| NCT02152449 |
Oral Nutritional Supplementation in Amyotrophic Lateral Sclerosis (ALS) Patients |
https://ClinicalTrials.gov/show/NCT02152449 |
Active, not recruiting |
University Hospital, Limoges |
2019-07-31 |
| NCT02118727 |
Therapy in Amyotrophic Lateral Sclerosis (TAME) |
https://ClinicalTrials.gov/show/NCT02118727 |
Recruiting |
University of Kansas Medical Center |
2022-10-31 |
| NCT02059759 |
Immuno-modulation in Amyotrophic Lateral Sclerosis- a Phase II Study of Safety and Activity of Low Dose Interleukin-2 |
https://ClinicalTrials.gov/show/NCT02059759 |
Completed |
Centre Hospitalier Universitaire de NÄ«mes |
2015-12-31 |
| NCT01285583 |
Safety Extension Study of TRO19622 in ALS |
https://ClinicalTrials.gov/show/NCT01285583 |
Completed |
Hoffmann-La Roche |
2012-03-31 |
| NCT01281631 |
A Study of NP001 in Subjects With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01281631 |
Completed |
Neuraltus Pharmaceuticals, Inc. |
2012-09-30 |
| NCT01281189 |
Phase 3 Study of Dexpramipexole in ALS |
https://ClinicalTrials.gov/show/NCT01281189 |
Completed |
Knopp Biosciences |
2012-11-30 |
| NCT02039401 |
Safety Study of VM202 to Treat Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT02039401 |
Completed |
Helixmith Co., Ltd. |
2015-09-30 |
| NCT02017912 |
Phase 2, Randomized, Double Blind, Placebo Controlled Multicenter Study of Autologous MSC-NTF Cells in Patients With ALS |
https://ClinicalTrials.gov/show/NCT02017912 |
Completed |
Brainstorm-Cell Therapeutics |
2016-03-31 |
| NCT01995903 |
Developing a Discrimination Model to Diagnose ALS |
https://ClinicalTrials.gov/show/NCT01995903 |
Completed |
University of Michigan |
2015-10-31 |
| NCT01951924 |
LIME Study (LFB IVIg MMN Efficacy Study) |
https://ClinicalTrials.gov/show/NCT01951924 |
Completed |
Laboratoire français de Fractionnement et de Biotechnologies |
2016-07-31 |
| NCT01933321 |
Effect of Intrathecal Administration of Hematopoietic Stem Cells in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01933321 |
Completed |
Hospital Universitario Dr. Jose E. Gonzalez |
2014-01-31 |
| NCT01906658 |
A Study to Explore the Safety and Tolerability of Acthar in Patients With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT01906658 |
Completed |
Mallinckrodt |
2014-11-30 |
| NCT01900132 |
Electrical Impedance Myography: Exploratory Studies in Healthy People and People With Neuromuscular Disorders |
https://ClinicalTrials.gov/show/NCT01900132 |
Recruiting |
National Institutes of Health Clinical Center (CC) |
2023-01-01 |
| NCT01884571 |
Immunosuppression in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01884571 |
Completed |
Emory University |
2016-01-31 |
| NCT01879241 |
Study of Rasagiline in Patients With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT01879241 |
Completed |
University of Ulm |
2016-04-30 |
| NCT01854294 |
GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS) |
https://ClinicalTrials.gov/show/NCT01854294 |
Completed |
Genervon Biopharmaceuticals, LLC |
2014-04-30 |
| NCT01849770 |
Mexiletine in Sporadic Amyotrophic Lateral Sclerosis (SALS) |
https://ClinicalTrials.gov/show/NCT01849770 |
Completed |
University of Washington |
2014-08-31 |
| NCT01825551 |
The Effect of GCSF in the Treatment of ALS Patients |
https://ClinicalTrials.gov/show/NCT01825551 |
Completed |
Tehran University of Medical Sciences |
2013-11-30 |
| NCT01823380 |
Influence of the Vitamin D Blood Levels on the Amyotrophic Lateral Sclerosis Phenotype |
https://ClinicalTrials.gov/show/NCT01823380 |
Completed |
University Hospital, Montpellier |
2014-02-28 |
| NCT01811355 |
Mexiletine for the Treatment of Muscle Cramps in ALS |
https://ClinicalTrials.gov/show/NCT01811355 |
Completed |
University of California, Davis |
2016-03-31 |
| NCT01806857 |
Clinical Trial Nuedexta in Subjects With ALS |
https://ClinicalTrials.gov/show/NCT01806857 |
Completed |
Center for Neurologic Study, La Jolla, California, |
2015-03-31 |
| NCT01786603 |
Rasagiline in Subjects With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01786603 |
Completed |
University of Kansas Medical Center |
2016-07-27 |
| NCT01777646 |
Autologous Mesenchymal Bone Marrow Stromal Cells Secreting Neurotrophic Factors (MSC-NTF), in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01777646 |
Completed |
Brainstorm-Cell Therapeutics |
2014-09-30 |
| NCT01776970 |
Safety and Efficacy on Spasticity Symptoms of a Cannabis Sativa Extract in Motor Neuron Disease |
https://ClinicalTrials.gov/show/NCT01776970 |
Completed |
Ospedale San Raffaele |
2015-12-31 |
| NCT01759797 |
Intravenous Transplantation of Mesenchymal Stem Cell in Patients With ALS |
https://ClinicalTrials.gov/show/NCT01759797 |
Completed |
Royan Institute |
2014-01-31 |
| NCT01758510 |
Safety Study of HLA-haplo Matched Allogenic Bone Marrow Derived Stem Cell Treatment in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT01758510 |
Completed |
Hanyang University Seoul Hospital |
2017-04-10 |
| NCT01753076 |
Study of Ozanezumab (GSK1223249) Versus Placebo in the Treatment of Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT01753076 |
Completed |
GlaxoSmithKline |
2015-01-22 |
| NCT01746381 |
Non-invasive Ventilation in Amyotrophic Lateral Sclerosis (ALS) Using the iVAPS Mode |
https://ClinicalTrials.gov/show/NCT01746381 |
Completed |
McGill University Health Centre/Research Institute of the McGill University Health Centre |
2019-12-31 |
| NCT01709149 |
Study of Safety, Tolerability & Efficacy of CK-2017357 in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01709149 |
Completed |
Cytokinetics |
2014-03-31 |
| NCT01641965 |
Impact of Early Non Invasive Ventilation in Amyotrophic Lateral Sclerosis (ALS) Patients |
https://ClinicalTrials.gov/show/NCT01641965 |
Completed |
Hospital Universitari de Bellvitge |
2015-12-31 |
| NCT01640067 |
Human Neural Stem Cell Transplantation in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01640067 |
Completed |
Azienda Ospedaliera Santa Maria, Terni, Italy |
2015-12-31 |
| NCT01639391 |
Creation of a Bank of Fibroblast From Patients With Amyotrophic Lateral Sclerosis: Pilot Study |
https://ClinicalTrials.gov/show/NCT01639391 |
Completed |
Institut Pasteur |
2015-03-17 |
| NCT01609283 |
A Dose-escalation Safety Trial for Intrathecal Autologous Mesenchymal Stem Cell Therapy in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT01609283 |
Completed |
Mayo Clinic |
2019-01-31 |
| NCT01605006 |
Humanitarian Device Exemption Post-Approval Study of NeuRx Diaphragm Pacing System for Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT01605006 |
Completed |
Synapse Biomedical |
2017-02-28 |
| NCT01551940 |
Toxin Treatment for Amyotrophic Lateral Sclerosis (ALS) Related Sialorrhea |
https://ClinicalTrials.gov/show/NCT01551940 |
Completed |
Hospices Civils de Lyon |
2014-03-31 |
| NCT01536249 |
Dexpramipexole and Cimetidine Drug Drug Interaction (DDI) |
https://ClinicalTrials.gov/show/NCT01536249 |
Completed |
Knopp Biosciences |
2012-04-30 |
| NCT01521728 |
Trial of Resistance and Endurance Exercise in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01521728 |
Completed |
Johns Hopkins University |
2016-02-29 |
| NCT01511029 |
Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate) |
https://ClinicalTrials.gov/show/NCT01511029 |
Completed |
Knopp Biosciences |
2012-05-31 |
| NCT01504009 |
Muscle Training of Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01504009 |
Completed |
University of Southern Denmark |
2012-12-31 |
| NCT01492686 |
Phase 3 Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT01492686 |
Completed |
Mitsubishi Tanabe Pharma Corporation |
2014-09-30 |
| NCT01486849 |
Dose Titration Study to Test Safety and Effects of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01486849 |
Completed |
Cytokinetics |
2012-03-31 |
| NCT01449578 |
Dexpramipexole SAD/MAD Study |
https://ClinicalTrials.gov/show/NCT01449578 |
Completed |
Knopp Biosciences |
2012-01-31 |
| NCT01424163 |
Dexpramipexole Japanese PK Study |
https://ClinicalTrials.gov/show/NCT01424163 |
Completed |
Knopp Biosciences |
2012-02-29 |
| NCT01378676 |
A Study to Evaluate the Effects of Multiple Doses of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01378676 |
Completed |
Cytokinetics |
2012-03-31 |
| NCT01369901 |
Effect of Functional Exercise in Patients With Spinal Bulbar Muscular Atrophy |
https://ClinicalTrials.gov/show/NCT01369901 |
Completed |
National Institutes of Health Clinical Center (CC) |
NA |
| NCT01363401 |
Safety and Efficacy Study of Autologous Bone Marrow Derived Stem Cell Treatment in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT01363401 |
Completed |
Corestem, Inc. |
2013-05-31 |
| NCT04393467 |
Transcranial Static Magnetic Field Stimulation (tSMS) in Amyotrophic Lateral Sclerosis (ALS). |
https://ClinicalTrials.gov/show/NCT04393467 |
Recruiting |
Campus Bio-Medico University |
2023-05-31 |
| NCT04313166 |
Treatment Continuation Study for Patients With ALS/MND Who Completed Study CMD-2019-001 |
https://ClinicalTrials.gov/show/NCT04313166 |
Recruiting |
Collaborative Medicinal Development Pty Limited |
2021-10-30 |
| NCT04302870 |
Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial |
https://ClinicalTrials.gov/show/NCT04302870 |
Recruiting |
University of Edinburgh |
2026-09-30 |
| NCT04293484 |
Cortico-Spinal tDCS as Rehabilitative Intervention in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT04293484 |
Recruiting |
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia |
2020-12-31 |
| NCT04254913 |
Clinical Pharmacology Study of Oral Edaravone in Amyotrophic Lateral Sclerosis Patients With Gastrostomy |
https://ClinicalTrials.gov/show/NCT04254913 |
Recruiting |
Mitsubishi Tanabe Pharma Corporation |
2020-07-31 |
| NCT04248465 |
An Efficacy and Safety Study of Ravulizumab in ALS Participants |
https://ClinicalTrials.gov/show/NCT04248465 |
Recruiting |
Alexion Pharmaceuticals |
2022-09-30 |
| NCT04245709 |
Clenbuterol on Motor Function in Individuals With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT04245709 |
Recruiting |
Duke University |
2021-02-10 |
| NCT04240925 |
Tolerability, Safety and Efficacy of Sigh Breaths During NIMV in Motor Neuron Disease |
https://ClinicalTrials.gov/show/NCT04240925 |
Recruiting |
Ospedale San Raffaele |
2020-12-31 |
| NCT04226144 |
Breath Stacking Technique Associated With Expiratory Muscle Training in Amyotrophic Lateral Sclerosis Patients |
https://ClinicalTrials.gov/show/NCT04226144 |
Recruiting |
Escola Superior de Ciencias da Saude |
2021-08-31 |
| NCT04220021 |
Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD |
https://ClinicalTrials.gov/show/NCT04220021 |
Recruiting |
University of Florida |
2021-05-31 |
| NCT04176224 |
Clinical Pharmacology Study of Oral Edaravone in Patients With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT04176224 |
Completed |
Mitsubishi Tanabe Pharma Corporation |
2019-09-04 |
| NCT04172792 |
Safety and Tolerability Ultra-high-caloric Food Supplements in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT04172792 |
Recruiting |
University of Ulm |
2020-11-25 |
| NCT04165850 |
Open Label Study to Evaluate Ciprofloxacin/Celecoxib Combination in Patients With ALS |
https://ClinicalTrials.gov/show/NCT04165850 |
Active, not recruiting |
NeuroSense Therapeutics Ltd. |
2020-02-29 |
| NCT04140136 |
The Efficacy and Safety of Vitamin E Mixed Tocotrienols In Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT04140136 |
Recruiting |
University of Malaya |
2020-04-01 |
| NCT04098406 |
Therapeutic Nanocatalysis to Slow Disease Progression of Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT04098406 |
Recruiting |
Clene Nanomedicine |
2021-04-30 |
| NCT04090684 |
Ciprofloxacin/Celecoxib Combination in Patients With ALS |
https://ClinicalTrials.gov/show/NCT04090684 |
Recruiting |
NeuroSense Therapeutics Ltd. |
2020-12-31 |
| NCT04082832 |
CuATSM Compared With Placebo for Treatment of ALS/MND |
https://ClinicalTrials.gov/show/NCT04082832 |
Recruiting |
Collaborative Medicinal Development Pty Limited |
2020-12-30 |
| NCT04066244 |
Study of Safety and of the Mechanism of BLZ945 in ALS Patients |
https://ClinicalTrials.gov/show/NCT04066244 |
Recruiting |
Novartis |
2021-02-11 |
| NCT04057898 |
Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS |
https://ClinicalTrials.gov/show/NCT04057898 |
Recruiting |
MediciNova |
2023-12-31 |
| NCT04055623 |
T-regulatory Cells in ALS |
https://ClinicalTrials.gov/show/NCT04055623 |
Active, not recruiting |
The Methodist Hospital System |
2024-09-01 |
| NCT03986671 |
Transmembrane Electromyography (TM-EMG) for the Assessment of Neuromuscular Function in the Oropharynx |
https://ClinicalTrials.gov/show/NCT03986671 |
Recruiting |
Powell Mansfield Inc. |
2020-10-31 |
| NCT03981536 |
A Study to Evaluate AP-101 in Familial and Sporadic Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT03981536 |
Recruiting |
AL-S Pharma |
2020-08-31 |
| NCT03975608 |
Psychological Therapy for Patients With ALS |
https://ClinicalTrials.gov/show/NCT03975608 |
Active, not recruiting |
University of Leipzig |
2020-07-31 |
| NCT03948178 |
Effects of Oral Levosimendan on Respiratory Function in Patients With ALS: Open-Label Extension |
https://ClinicalTrials.gov/show/NCT03948178 |
Recruiting |
Orion Corporation, Orion Pharma |
2022-07-31 |
| NCT03945279 |
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB100 Administered Orally to Adults With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03945279 |
Recruiting |
Biogen |
2020-12-31 |
| NCT03944447 |
Outcomes Mandate National Integration With Cannabis as Medicine |
https://ClinicalTrials.gov/show/NCT03944447 |
Recruiting |
OMNI Medical Services, LLC |
2025-12-31 |
| NCT03900247 |
Restore Motor Function Through Robotic Arm Exoskeleton and Brain Computer Interface |
https://ClinicalTrials.gov/show/NCT03900247 |
Enrolling by invitation |
University of Aarhus |
2021-12-31 |
| NCT03887338 |
Systematic Laryngoscopic Evaluation of Upper Airways in Ventilated ALS Patients in Portugal and in Norway |
https://ClinicalTrials.gov/show/NCT03887338 |
Recruiting |
Haukeland University Hospital |
2021-12-31 |
| NCT03883581 |
Impact of Nuedexta on Bulbar Physiology and Function in ALS |
https://ClinicalTrials.gov/show/NCT03883581 |
Recruiting |
University of Florida |
2020-12-01 |
| NCT03876002 |
Evaluation of Microglial Activation in ALS With [18F]PBR06 (Peripheral Benzodiazepine Receptor-06) PET |
https://ClinicalTrials.gov/show/NCT03876002 |
Completed |
Molecular NeuroImaging |
2018-02-07 |
| NCT03836716 |
Arimoclomol in Amyotropic Lateral Sclerosis - Open Label Extension Trial |
https://ClinicalTrials.gov/show/NCT03836716 |
Enrolling by invitation |
Orphazyme |
2022-08-01 |
| NCT03835507 |
Randomized, Double-blind, Safety and Efficacy of Recombinant Human Erythropoietin in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03835507 |
Recruiting |
Hanyang University Seoul Hospital |
2020-12-31 |
| NCT03828123 |
Autologous Multipotent Mesenchymal Stromal Cells in the Treatment of Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03828123 |
Completed |
Bioinova, s.r.o. |
2017-08-18 |
| NCT03811301 |
[BrainConnexion] - Neurodevice Phase II Trial |
https://ClinicalTrials.gov/show/NCT03811301 |
Recruiting |
National Neuroscience Institute |
2021-12-31 |
| NCT03809845 |
Serial Fasciculation Measurements in Motor Neurone Disease |
https://ClinicalTrials.gov/show/NCT03809845 |
Completed |
King’s College Hospital NHS Trust |
2019-03-01 |
| NCT03800524 |
Safety and Efficacy of TUDCA as add-on Treatment in Patients Affected by ALS |
https://ClinicalTrials.gov/show/NCT03800524 |
Recruiting |
Humanitas Mirasole SpA |
2021-06-30 |
| NCT03797677 |
MN4000 for Treatment of CF and MND Patients in the Home Setting |
https://ClinicalTrials.gov/show/NCT03797677 |
Completed |
Hill-Rom |
2017-11-30 |
| NCT03793868 |
Perampanel Single Ascending Dose Transcranial Magnetic Stimulation Biomarker Study in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03793868 |
Recruiting |
Mayo Clinic |
2020-08-01 |
| NCT03792490 |
Inhibition of Rho Kinase (ROCK) With Fasudil as Disease-modifying Treatment for ALS |
https://ClinicalTrials.gov/show/NCT03792490 |
Recruiting |
University Medical Center Goettingen |
2021-10-31 |
| NCT03787420 |
Development and Needs Assessment and Efficiency of Smart Communication System for Patients With ALS. |
https://ClinicalTrials.gov/show/NCT03787420 |
Recruiting |
Taipei Veterans General Hospital, Taiwan |
2019-08-31 |
| NCT03757351 |
Study to Evaluate DNL747 in Subjects With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03757351 |
Active, not recruiting |
Sanofi |
2020-03-12 |
| NCT03755167 |
A Follow up Study to Protocol 101/2 - Continued Treatment by IPL344 IV |
https://ClinicalTrials.gov/show/NCT03755167 |
Recruiting |
Immunity Pharma Ltd. |
2022-11-30 |
| NCT03707795 |
Treatment of FUS-Related ALS With Betamethasone - The TRANSLATE Study |
https://ClinicalTrials.gov/show/NCT03707795 |
Completed |
University of Kentucky |
2019-01-10 |
| NCT03705390 |
A Safety and Tolerability Study of ILB in Patients With Amyothrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT03705390 |
Recruiting |
University of Birmingham |
2021-04-29 |
| NCT03694132 |
Brain Excitability and Connectivity in Sensory-motor Pathways in ALS |
https://ClinicalTrials.gov/show/NCT03694132 |
Recruiting |
Institut National de la Santé Et de la Recherche Médicale, France |
2019-12-31 |
| NCT03693781 |
Colchicine for Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03693781 |
Recruiting |
Azienda Ospedaliero-Universitaria di Modena |
2021-10-01 |
| NCT03690791 |
Efficacy of Cannabinoids in Amyotrophic Lateral Sclerosis or Motor Neurone Disease |
https://ClinicalTrials.gov/show/NCT03690791 |
Recruiting |
Gold Coast Hospital and Health Service |
2021-12-31 |
| NCT03652805 |
A Study of IPL344 in the Treatment of ALS Patients |
https://ClinicalTrials.gov/show/NCT03652805 |
Recruiting |
Immunity Pharma Ltd. |
2020-07-15 |
| NCT03645031 |
Acute Intermittent Hypoxia and Breathing in Neuromuscular Disease |
https://ClinicalTrials.gov/show/NCT03645031 |
Recruiting |
University of Florida |
2021-03-31 |
| NCT03626012 |
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB078 in Adults With C9ORF72-Associated Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03626012 |
Active, not recruiting |
Biogen |
2021-09-28 |
| NCT03618966 |
Neuromuscular Magnetic Stimulation in ALS Patients |
https://ClinicalTrials.gov/show/NCT03618966 |
Completed |
University of Roma La Sapienza |
2016-05-01 |
| NCT03613038 |
A Systematic Investigation of Phonetic Complexity Effects on Articulatory Motor Performance in Progressive Dysarthria |
https://ClinicalTrials.gov/show/NCT03613038 |
Recruiting |
University of Missouri-Columbia |
2020-01-31 |
| NCT03604822 |
Music Therapy Protocol to Support Bulbar and Respiratory Functions in ALS |
https://ClinicalTrials.gov/show/NCT03604822 |
Active, not recruiting |
Anglia Ruskin University |
2018-07-31 |
| NCT03580616 |
Tolerability and Efficacy of L-Serine in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT03580616 |
Recruiting |
Dartmouth-Hitchcock Medical Center |
2022-06-30 |
| NCT03573466 |
Presymptomatic Neuromuscular Junction Defects and Compensatory Mechanisms in ALS |
https://ClinicalTrials.gov/show/NCT03573466 |
Active, not recruiting |
Assistance Publique - Hôpitaux de Paris |
2021-04-10 |
| NCT03567213 |
Investigation on the Cortical Communication (CortiCom) System |
https://ClinicalTrials.gov/show/NCT03567213 |
Recruiting |
Johns Hopkins University |
2024-11-30 |
| NCT03545451 |
Neurofeedback Rehabilitation Based on Motor Imaging in Patients in the Immobilization Phase |
https://ClinicalTrials.gov/show/NCT03545451 |
Recruiting |
Assistance Publique - Hôpitaux de Paris |
2021-06-30 |
| NCT03520517 |
Open-label Study to Evaluate Safety, Tolerability and PK of BHV-0223 in ALS |
https://ClinicalTrials.gov/show/NCT03520517 |
Completed |
Biohaven Pharmaceuticals, Inc. |
2018-10-08 |
| NCT03516994 |
Reducing Disparities in the Quality of Advance Care Planning for Older Adults |
https://ClinicalTrials.gov/show/NCT03516994 |
Enrolling by invitation |
Duke University |
2022-09-01 |
| NCT03506425 |
A Pilot Trial of Triheptanoin for People With Amyotrophic Lateral Sclerosis (PALS) |
https://ClinicalTrials.gov/show/NCT03506425 |
Completed |
Duke University |
2019-03-28 |
| NCT03505021 |
Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALS |
https://ClinicalTrials.gov/show/NCT03505021 |
Active, not recruiting |
Orion Corporation, Orion Pharma |
2020-08-30 |
| NCT03491462 |
Arimoclomol in Amyotropic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03491462 |
Active, not recruiting |
Orphazyme |
2020-12-31 |
| NCT03489200 |
EH301 for the Treatment of ALS |
https://ClinicalTrials.gov/show/NCT03489200 |
Completed |
Elysium Health |
2017-06-30 |
| NCT03488524 |
Open Label Extension Study of AMX0035 in Patients With ALS |
https://ClinicalTrials.gov/show/NCT03488524 |
Enrolling by invitation |
Amylyx Pharmaceuticals Inc. |
2021-01-01 |
| NCT03487263 |
Dose-Escalation, Safety and Pharmacokinetic Study of IC14 in Motor Neurone Disease |
https://ClinicalTrials.gov/show/NCT03487263 |
Completed |
Implicit Bioscience |
2018-04-18 |
| NCT03482050 |
A Study to Evaluate Transplantation of Astrocytes Derived From Human Embryonic Stem Cells, in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT03482050 |
Recruiting |
Kadimastem |
2020-11-30 |
| NCT03481348 |
Pharyngeal Electrical Stimulation in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03481348 |
Recruiting |
University of Ulm |
2020-02-28 |
| NCT03472950 |
Safety and Efficacy of Ranolazine for the Treatment of Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT03472950 |
Recruiting |
University of Kansas Medical Center |
2019-10-01 |
| NCT03456882 |
The Effect of RNS60 on ALS Biomarkers |
https://ClinicalTrials.gov/show/NCT03456882 |
Active, not recruiting |
Mario Negri Institute for Pharmacological Research |
2020-04-30 |
| NCT03452618 |
Predictive Factors for the Diagnosis of Early Noninvasive Ventilation Equipment |
https://ClinicalTrials.gov/show/NCT03452618 |
Recruiting |
University Hospital, Toulouse |
2019-11-30 |
| NCT03411863 |
Cervical Electrical Stimulation for ALS |
https://ClinicalTrials.gov/show/NCT03411863 |
Active, not recruiting |
VA Office of Research and Development |
2021-01-31 |
| NCT01259050 |
Safety Study of High Doses of Zinc in ALS Patients |
https://ClinicalTrials.gov/show/NCT01259050 |
Completed |
Phoenix Neurological Associates, LTD |
2012-01-31 |
| NCT01257581 |
Safety and Efficacy Study of Creatine and Tamoxifen in Volunteers With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01257581 |
Completed |
Massachusetts General Hospital |
2012-12-31 |
| NCT01254539 |
Clinical Trial on The Use of Autologous Bone Marrow Stem Cells in Amyotrophic Lateral Sclerosis (Extension CMN/ELA) |
https://ClinicalTrials.gov/show/NCT01254539 |
Completed |
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia |
2015-11-20 |
| NCT01232738 |
Trial of Safety and Efficacy of Rasagiline in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01232738 |
Completed |
University of Kansas Medical Center |
2013-05-31 |
| NCT01160367 |
Trial of Ascertaining Individual Preferences for Loved One’s Role in End-of-Life |
https://ClinicalTrials.gov/show/NCT01160367 |
Completed |
Johns Hopkins University |
2014-03-26 |
| NCT01160263 |
Study of Dopamine and Serotonin Transporters in Patients With Amyotrophic Lateral Sclerosis and Controls |
https://ClinicalTrials.gov/show/NCT01160263 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2014-10-31 |
| NCT01154283 |
Study of Standard Noninvasive Positive Pressure Ventilation (NIPPV) and Low Expiratory Pressure NIPPV in ALS Patients |
https://ClinicalTrials.gov/show/NCT01154283 |
Completed |
University of Michigan |
2011-10-31 |
| NCT01142856 |
Mesenchymal Stem Cells for Treatment of Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01142856 |
Completed |
Mayo Clinic |
2011-04-30 |
| NCT01123200 |
An In-home Study of Brain Computer Interfaces |
https://ClinicalTrials.gov/show/NCT01123200 |
Completed |
University of Michigan |
2011-05-31 |
| NCT01123148 |
A P300 Brain Computer Interface to Operate Power Wheelchair Tilt |
https://ClinicalTrials.gov/show/NCT01123148 |
Completed |
University of Michigan |
2010-08-31 |
| NCT01119001 |
A P300 Brain Computer Interface Keyboard to Control Assistive Technology For Use by People With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT01119001 |
Completed |
University of Michigan |
2010-08-31 |
| NCT01091142 |
Single-Ascending-Dose Safety/Tolerability of NP001 in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01091142 |
Completed |
Neuraltus Pharmaceuticals, Inc. |
2010-09-30 |
| NCT01089010 |
A Study of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01089010 |
Completed |
Cytokinetics |
2010-11-30 |
| NCT01083667 |
SOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01083667 |
Completed |
Weill Medical College of Cornell University |
2014-12-31 |
| NCT01051882 |
Autologous Cultured Mesenchymal Bone Marrow Stromal Cells Secreting Neurotrophic Factors (MSC-NTF), in ALS Patients. |
https://ClinicalTrials.gov/show/NCT01051882 |
Completed |
Brainstorm-Cell Therapeutics |
2012-12-31 |
| NCT01041222 |
Safety, Tolerability, and Activity Study of ISIS SOD1Rx to Treat Familial Amyotrophic Lateral Sclerosis (ALS) Caused by SOD1 Gene Mutations |
https://ClinicalTrials.gov/show/NCT01041222 |
Completed |
Ionis Pharmaceuticals, Inc. |
2011-12-31 |
| NCT01020331 |
Memantine Therapy in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT01020331 |
Completed |
Phoenix Neurological Associates, LTD |
2009-07-31 |
| NCT00983983 |
High Fat/High Calorie Trial in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00983983 |
Completed |
Massachusetts General Hospital |
2013-04-30 |
| NCT00965497 |
Escitalopram (Lexapro) for Depression MS or ALS |
https://ClinicalTrials.gov/show/NCT00965497 |
Completed |
University of South Carolina |
2010-03-31 |
| NCT00958048 |
Effects of Nocturnal Non-invasive Ventilation in Patients With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00958048 |
Completed |
National Taiwan University Hospital |
2013-04-30 |
| NCT00956488 |
Supported Treadmill Ambulation Training (STAT) for Patients Diagnosed With Amyotrophic Lateral Aclerosis |
https://ClinicalTrials.gov/show/NCT00956488 |
Completed |
Atrium Health |
2010-09-30 |
| NCT00931944 |
Open-Label, Safety and Tolerability Extension Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) (CL211) |
https://ClinicalTrials.gov/show/NCT00931944 |
Completed |
Knopp Biosciences |
2013-07-31 |
| NCT00925847 |
Effect of Lithium Carbonate in Patients With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00925847 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2011-04-30 |
| NCT00919555 |
Combination Therapy in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00919555 |
Completed |
Phoenix Neurological Associates, LTD |
2009-11-30 |
| NCT00912041 |
BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia |
https://ClinicalTrials.gov/show/NCT00912041 |
Recruiting |
Massachusetts General Hospital |
2022-09-30 |
| NCT00879593 |
Nocturnal PtcCO2 Monitoring in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00879593 |
Completed |
Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche |
2014-06-30 |
| NCT00877604 |
Efficacy and Tolerability of Tauroursodeoxycholic Acid in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00877604 |
Completed |
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta |
2011-07-31 |
| NCT00875446 |
First Time in Human Study of GSK1223249 in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00875446 |
Completed |
GlaxoSmithKline |
2011-09-09 |
| NCT00868166 |
Safety and Efficacy of TRO19622 as add-on Therapy to Riluzole Versus Placebo in Treatment of Patients Suffering From ALS |
https://ClinicalTrials.gov/show/NCT00868166 |
Completed |
Hoffmann-La Roche |
2011-09-30 |
| NCT00860951 |
P300 Brain Computer Interface Keyboard to Operate Assistive Technology |
https://ClinicalTrials.gov/show/NCT00860951 |
Completed |
University of Michigan |
2012-05-31 |
| NCT00855400 |
Clinical Trial on the Use of Autologous Bone Marrow Stem Cells in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00855400 |
Completed |
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia |
2009-10-31 |
| NCT00847847 |
Neuromuscular Transmission in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00847847 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2012-04-30 |
| NCT03237741 |
Bioavailability of GDC-0134 and the Effect of Food and Proton Pump Inhibitor on Pharmacokinetics of GDC-0134 in Healthy Female Participants |
https://ClinicalTrials.gov/show/NCT03237741 |
Completed |
Genentech, Inc. |
2017-12-14 |
| NCT00833820 |
Repetitive Transcranial Magnetic Stimulation (rTMS) in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00833820 |
Completed |
Catholic University of the Sacred Heart |
2008-12-31 |
| NCT00812851 |
Randomized Placebo-Controlled Crossover Trial With THC (Delta 9-Tetrahydrocannabinol) for the Treatment of Cramps in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00812851 |
Completed |
Cantonal Hospital of St. Gallen |
2008-04-30 |
| NCT01786174 |
Gilenya in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT01786174 |
Completed |
Massachusetts General Hospital |
2014-09-30 |
| NCT01771640 |
Intrathecal Transplantation of Mesenchymal Stem Cell in Patients With ALS |
https://ClinicalTrials.gov/show/NCT01771640 |
Completed |
Royan Institute |
2014-10-31 |
| NCT01424176 |
Dexpramipexole Renal PK Study |
https://ClinicalTrials.gov/show/NCT01424176 |
Completed |
Knopp Biosciences |
2012-01-31 |
| NCT03154450 |
EncoreAnywhere Use in Motor Neurone Disease |
https://ClinicalTrials.gov/show/NCT03154450 |
Completed |
Sheffield Teaching Hospitals NHS Foundation Trust |
2017-04-01 |
| NCT03039673 |
MIROCALS: Modifying Immune Response and OutComes in ALS |
https://ClinicalTrials.gov/show/NCT03039673 |
Active, not recruiting |
Centre Hospitalier Universitaire de NÄ«mes |
2021-09-30 |
| NCT02709330 |
ALS Reversals - Lunasin Regimen |
https://ClinicalTrials.gov/show/NCT02709330 |
Completed |
Duke University |
2017-09-13 |
| NCT04326283 |
Trial of Safety, Tolerability and Efficacy of Trametinib (SNR1611) in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT04326283 |
Recruiting |
Genuv Inc. |
2022-03-31 |
| NCT00748501 |
Clinical Trial of SB-509 in Subjects With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00748501 |
Completed |
Sangamo Therapeutics |
2010-06-30 |
| NCT00706147 |
Phase II/III Randomized, Placebo-controlled Trial of Arimoclomol in SOD1 Positive Familial Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00706147 |
Completed |
University of Miami |
2014-12-31 |
| NCT00696332 |
Talampanel for Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00696332 |
Completed |
Teva Pharmaceutical Industries |
2010-04-30 |
| NCT00800501 |
A Safety and Tolerability Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00800501 |
Completed |
Newron Sweden AB |
2011-06-30 |
| NCT00647296 |
Safety and Tolerability Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00647296 |
Completed |
Knopp Biosciences |
2009-09-30 |
| NCT00635960 |
Growth Hormone in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00635960 |
Completed |
Federico II University |
2009-07-31 |
| NCT00613899 |
Feasibility of Telesurveillance and Home Cough Assistance for Amyotrophic Lateral Patients (ALS) |
https://ClinicalTrials.gov/show/NCT00613899 |
Completed |
Fondazione Salvatore Maugeri |
2008-03-31 |
| NCT00600873 |
R(+)PPX High Dose Treatment of ALS |
https://ClinicalTrials.gov/show/NCT00600873 |
Completed |
Bennett, James P., Jr., M.D., Ph.D. |
2008-09-30 |
| NCT00580593 |
Trial of Early Noninvasive Ventilation for Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00580593 |
Completed |
University of Michigan |
2012-03-31 |
| NCT00542412 |
CARE Canadian ALS Riluzole Evaluation |
https://ClinicalTrials.gov/show/NCT00542412 |
Completed |
Sanofi |
NA |
| NCT00445172 |
A Long-Term Study in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00445172 |
Completed |
Eisai Inc. |
2017-03-31 |
| NCT00444613 |
A Study in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00444613 |
Completed |
Eisai Inc. |
2014-03-31 |
| NCT00424463 |
Expanded Controlled Study of Safety and Efficacy of MCI-186 in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00424463 |
Completed |
Mitsubishi Tanabe Pharma Corporation |
2009-05-31 |
| NCT00415519 |
Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) Who Met Severity Classification III |
https://ClinicalTrials.gov/show/NCT00415519 |
Completed |
Mitsubishi Tanabe Pharma Corporation |
2008-07-31 |
| NCT00409721 |
The Effect of Memantine on Functional Outcomes and Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00409721 |
Completed |
University of Alberta |
2010-12-31 |
| NCT00403104 |
Placebo Controlled Study of ONO2506PO in the Presence of Riluzole in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00403104 |
Completed |
Ono Pharmaceutical Co. Ltd |
2008-12-31 |
| NCT00397423 |
G-CSF Treatment for Amyotrophic Lateral Sclerosis: A RCT Study Assessing Clinical Response |
https://ClinicalTrials.gov/show/NCT00397423 |
Completed |
Peking University |
NA |
| NCT00386464 |
Noninvasive Ventilation in ALS Patients With Mild Respiratory Involvement |
https://ClinicalTrials.gov/show/NCT00386464 |
Completed |
Johns Hopkins University |
NA |
| NCT00372879 |
Clinical Trial of Vitamin E to Treat Muscular Cramps in Patients With ALS |
https://ClinicalTrials.gov/show/NCT00372879 |
Completed |
Lawson Health Research Institute |
2010-08-31 |
| NCT00355576 |
Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00355576 |
Completed |
Columbia University |
NA |
| NCT00353665 |
Memantine for Disability in Amyotrophic Lateral Sclerosis (MEDALS) |
https://ClinicalTrials.gov/show/NCT00353665 |
Completed |
University of Lisbon |
2008-06-30 |
| NCT00349622 |
Clinical Trial Ceftriaxone in Subjects With ALS |
https://ClinicalTrials.gov/show/NCT00349622 |
Completed |
Massachusetts General Hospital |
2012-11-30 |
| NCT00330681 |
Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00330681 |
Completed |
Mitsubishi Tanabe Pharma Corporation |
2008-09-30 |
| NCT00326625 |
Clinical Trial of Glatiramer Acetate in Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00326625 |
Completed |
Teva Pharmaceutical Industries |
2008-06-30 |
| NCT00324454 |
Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease |
https://ClinicalTrials.gov/show/NCT00324454 |
Completed |
Duke University |
2007-12-31 |
| NCT00298597 |
Influence of G-CSF and EPO on Associative Learning and Motor Skills |
https://ClinicalTrials.gov/show/NCT00298597 |
Completed |
University Hospital Muenster |
2009-03-31 |
| NCT00244244 |
A Multicenter, Dose Ranging Safety and Pharmacokinetics Study of Arimoclomol in ALS |
https://ClinicalTrials.gov/show/NCT00244244 |
Completed |
CytRx |
2007-01-31 |
| NCT00243932 |
Clinical Trial of High Dose CoQ10 in ALS |
https://ClinicalTrials.gov/show/NCT00243932 |
Completed |
Columbia University |
2008-03-31 |
| NCT00230074 |
A Long-term Extension Study of TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis(ALS) |
https://ClinicalTrials.gov/show/NCT00230074 |
Completed |
Novartis |
2005-02-28 |
| NCT00214110 |
Tamoxifen Therapy in Amyotrophic Lateral Sclerosis [ALS] |
https://ClinicalTrials.gov/show/NCT00214110 |
Completed |
University of Wisconsin, Madison |
NA |
| NCT00204464 |
Study of the Effects Strengthening Exercises in Individuals With ALS |
https://ClinicalTrials.gov/show/NCT00204464 |
Completed |
University of Saskatchewan |
NA |
| NCT02414230 |
F 18 T807 Tau PET Imaging in Familial Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT02414230 |
Active, not recruiting |
Washington University School of Medicine |
2021-06-30 |
| NCT00140452 |
Phase II Study Using Thalidomide for the Treatment of ALS |
https://ClinicalTrials.gov/show/NCT00140452 |
Completed |
Dartmouth-Hitchcock Medical Center |
NA |
| NCT00140218 |
R(+) Pramipexole in Early Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00140218 |
Completed |
Bennett, James P., Jr., M.D., Ph.D. |
2007-01-31 |
| NCT00136110 |
Trial of Sodium Valproate in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00136110 |
Completed |
UMC Utrecht |
NA |
| NCT00125203 |
Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00125203 |
Completed |
The University of Texas Health Science Center at San Antonio |
NA |
| NCT00116558 |
Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure Ventilation |
https://ClinicalTrials.gov/show/NCT00116558 |
Completed |
University of Kentucky |
2012-01-31 |
| NCT00107770 |
Safety Study of Oral Sodium Phenylbutyrate in Subjects With ALS (Amyotrophic Lateral Sclerosis) |
https://ClinicalTrials.gov/show/NCT00107770 |
Completed |
VA Office of Research and Development |
2006-11-30 |
| NCT00076687 |
Safety Study of Botulinum Toxin Type A in Post-Upper Limb Stroke Patients With Reduced Lung Function |
https://ClinicalTrials.gov/show/NCT00076687 |
Completed |
Allergan |
2009-08-31 |
| NCT00072709 |
Study Evaluating TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00072709 |
Completed |
Novartis |
2004-12-31 |
| NCT00070993 |
Creatine for the Treatment of Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00070993 |
Completed |
National Center for Complementary and Integrative Health (NCCIH) |
NA |
| NCT00047723 |
Minocycline to Treat Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00047723 |
Completed |
National Institute of Neurological Disorders and Stroke (NINDS) |
NA |
| NCT00036413 |
A 12-week, Multicenter, Safety and Dose-ranging Study of 3 Oral Doses of TCH346 in Patients With Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00036413 |
Completed |
Novartis |
2002-10-31 |
| NCT00035815 |
Insulin-like Growth Factor-1 in Amyotrophic Lateral Sclerosis (ALS) Trial |
https://ClinicalTrials.gov/show/NCT00035815 |
Completed |
Mayo Clinic |
2007-08-31 |
| NCT00694941 |
A Phase II Multi-centre, Extension Study to Investigate the Long Term Safety of ONO-2506PO in Patients Diagnosed With Amyotrophic Lateral Sclerosis (ALS) |
https://ClinicalTrials.gov/show/NCT00694941 |
Completed |
Ono Pharmaceutical Co. Ltd |
2008-12-31 |
| NCT00021697 |
Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS |
https://ClinicalTrials.gov/show/NCT00021697 |
Completed |
Avanir Pharmaceuticals |
2002-04-30 |
| NCT00005766 |
Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis |
https://ClinicalTrials.gov/show/NCT00005766 |
Completed |
National Center for Research Resources (NCRR) |
NA |
| NCT00005674 |
Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis [ALS] |
https://ClinicalTrials.gov/show/NCT00005674 |
Completed |
National Center for Research Resources (NCRR) |
NA |
| NCT00004771 |
Phase II Study of Leuprolide and Testosterone for Men With Kennedy’s Disease or Other Motor Neuron Disease |
https://ClinicalTrials.gov/show/NCT00004771 |
Completed |
Office of Rare Diseases (ORD) |
NA |